Wrinkles appearing in areas such as the eye area, between the eyebrows, forehead and nose root as a result of factors such as genetic factors, aging, and excessive use of mimics can be removed with botox application in a short time and in a practical way. Botox applications, which show their effect by preventing the release of substances that provide conduction in the nerve endings and by stopping the transmission between the nerves and the organs reached by the nerves, can be used to reduce wrinkles on the face as well as to reduce sweating in areas with excessive sweating as well as to treat chronic migraine.